@article{oai:kpu.repo.nii.ac.jp:00005523, author = {田代, 操 and Tashiro, Misao and 倉田, 明枝 and Kurata, Akie and 小川, 久美 and Ogawa, Hisami}, journal = {京都府立大学学術報告. 理学・生活科学, The scientific reports of the Kyoto Prefectural University. Natural science and living science}, month = {Nov}, note = {幼ラットに20%カゼイン飼料を与えて14日間飼育した。その後さらにカゼイン含量が0,5,10,20,40%の飼料を与える群と飢餓群に分け2日間飼育した。飼料変動後の2日間において, 10%および40%カゼイン食変動群は10g以上の体重を増したがこれは20%カゼイン食群の値と同等であった。対照的に絶食群と無タンパク食群は体重を減少させた。平均肝湿重量に関しては, 5,10,40%カゼイン食群は20%カゼイン食群と同等の値を示し, 飢餓群や無タンパク食群より高い値を示した。肝カテプシンB, H, Lの総活性については, 10%および40%カゼイン食群が20%カゼイン食群と類似の値を示し, 無タンパク食群の値を上回っていた。また, 飢餓群の総活性は0%および5%カゼイン食群より高くなる傾向を示した。これらの結果より, ラットの肝カテプシン活性はタンパク質含量の異なる飼料変動によりすみやかに影響されることが示唆された。, Male weanling rats were fed a diet containing 20% casein for 14 days and divided into 6 groups. One group was starved for 2 days and the other 5 groups were fed either 0,5,10,20,or 40% casein diets for 2 days. During 2 days after a nutritional shift rats fed the 10 or 40% casein gained over 10g of body weight corresponding to that gained by rats fed the 20% casein. In contrast, rats with starvation and rats fed the protein-free diet lost weight. In animals fed the 5,10,or 40% casein diets, average liver weights were similar to that of rats given the 20% casein and higher than those of the starved rats and the rats consuming the 0% casein. Total activities of cathepsins B, H, and L in liver of rats fed the 10 or 40% casein were similar to those of rats fed the 20% casein and higher than those of rats fed the 0% casein. The total activities of the starved group tended to be higher than those of the 0 and 5% casein groups. These results suggest that cathepsin activities in rat liver are rapidly affected by alterations in the protein content of the diet.}, pages = {23--27}, title = {ラット肝カテプシン活性に及ぼす飼料変動の影響(B. 生活科学)}, volume = {44}, year = {1993}, yomi = {タシロ, ミサオ and クラタ, アキエ and オガワ, ヒサミ} }