{"created":"2023-06-19T08:46:19.102456+00:00","id":5108,"links":{},"metadata":{"_buckets":{"deposit":"34d59081-7725-4064-bdc0-c16e0f39980d"},"_deposit":{"created_by":14,"id":"5108","owners":[14],"pid":{"revision_id":0,"type":"depid","value":"5108"},"status":"published"},"_oai":{"id":"oai:kpu.repo.nii.ac.jp:00005108","sets":["47:273:427"]},"author_link":["9022","9032","7646","9031","8695"],"control_number":"5108","item_1696926521561":{"attribute_name":"その他（別言語等）","attribute_value_mlt":[{"subitem_alternative_title":"Detection of antihypertensive glycoprotein from chlorella (Agricultural Chemistry)","subitem_alternative_title_language":"en"}]},"item_3_biblio_info_12":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1983-11-15","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"143","bibliographicPageStart":"138","bibliographicVolumeNumber":"35","bibliographic_titles":[{"bibliographic_title":"京都府立大學學術報告. 農學","bibliographic_titleLang":"ja"},{"bibliographic_title":"The scientific reports of Kyoto Prefectural University. Agriculture","bibliographic_titleLang":"en"}]}]},"item_3_description_10":{"attribute_name":"抄録(日)","attribute_value_mlt":[{"subitem_description":"クロレラから, 血圧降下作用物質が部分精製された。生クロレラの細胞壁破砕物を冷アセトンにて脱脂脱色後, 冷水抽出物が得られた。冷水抽出物の80%エタノール不溶性画分に降圧作用が認められた。80%エタノール不溶性画分のBio-Gel P-60ゲルロ過, DEAE-セルロースクロマトグラフィーにより, ほぼ均一な降圧画分D-IIが得られた。画分D-IIの分子量は, 約80,000と推定された。画分D-IIを, 13週令の血圧180∿190mmHgのSHRに0.5mg/100g体重の割合で腹腔内投与すると, 1時間後に140∿160mmHgという血圧になり, 強い降圧効果が認められた。画分D-IIは, ガラクトース, マンノース, グルコサミンを含む糖蛋白質で, アスパラギン酸, グルタミン酸, アラニン, プロリンの含量が高く, 塩基性アミノ酸が少なかった。","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_3_description_11":{"attribute_name":"抄録(英)","attribute_value_mlt":[{"subitem_description":"The antihypertensive material was partially purified from chlorella. Cell wall of chlorella was destroyed with Dyno-mill. After defatted and decolored with cold aceton, water extract was obtained from chlorella by the extraction at 4℃ for 24 hours. 80% ethanol precipitate from water extract was fractionated by Bio-Gel P-60 gel filtration followed by DEAE-cellulose chromatatography. About 50mg of antihypertensive fraction D-II were obtained from 10g of chlorella. The molecular weight of fraction D-II was about 80,000 dalton. The blood pressure of spontaneously hypertensive rat (13 weeks of age) was decreased from 185 to 150mmHg, when fraction D-II was injected intraperitoneally at the concentration of 0.5mg/100g of body weight. Fraction D-II contained galactose, mannose and glucosamine. The contents of aspartic acid, glutamic acid, alanine and proline in fraction D-II were large.","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_3_source_id_1":{"attribute_name":"雑誌書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AN00062275","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_20":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00757373","subitem_source_identifier_type":"PISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"土井, 裕司","creatorNameLang":"ja"},{"creatorName":"ドイ, ヒロシ","creatorNameLang":"ja-Kana"},{"creatorName":"Doi, Hiroshi","creatorNameLang":"en"}],"familyNames":[{},{},{}],"givenNames":[{},{},{}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"島, 宗宏","creatorNameLang":"ja"},{"creatorName":"シマ, ムネヒロ","creatorNameLang":"ja-Kana"},{"creatorName":"Shima, Munehiro","creatorNameLang":"en"}],"familyNames":[{},{},{}],"givenNames":[{},{},{}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"河端, 康","creatorNameLang":"ja"},{"creatorName":"カワバタ, ヤスシ","creatorNameLang":"ja-Kana"},{"creatorName":"Kawabata, Yasushi","creatorNameLang":"en"}],"familyNames":[{},{},{}],"givenNames":[{},{},{}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"頼田, 正信","creatorNameLang":"ja"},{"creatorName":"ヨリタ, マサノブ","creatorNameLang":"ja-Kana"},{"creatorName":"Yorita, Masanobu","creatorNameLang":"en"}],"familyNames":[{},{},{}],"givenNames":[{},{},{}],"nameIdentifiers":[{}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[],"affiliationNames":[{"affiliationName":""}]}],"creatorNames":[{"creatorName":"金森, 正雄","creatorNameLang":"ja"},{"creatorName":"カナモリ, マサオ","creatorNameLang":"ja-Kana"},{"creatorName":"Kanamori, Masao","creatorNameLang":"en"}],"familyNames":[{},{},{}],"givenNames":[{},{},{}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-02-20"}],"displaytype":"detail","filename":"KJ00000079107.pdf","filesize":[{"value":"424.2 kB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"label":"KJ00000079107.pdf","url":"https://kpu.repo.nii.ac.jp/record/5108/files/KJ00000079107.pdf"},"version_id":"8ca710aa-347a-442c-8c71-87bb850caeb1"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper"}]},"item_title":"クロレラからの血圧降下作用糖蛋白質の検索(農芸化学部門)","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"クロレラからの血圧降下作用糖蛋白質の検索(農芸化学部門)","subitem_title_language":"ja"}]},"item_type_id":"3","owner":"14","path":["427"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2017-02-20"},"publish_date":"2017-02-20","publish_status":"0","recid":"5108","relation_version_is_last":true,"title":["クロレラからの血圧降下作用糖蛋白質の検索(農芸化学部門)"],"weko_creator_id":"14","weko_shared_id":-1},"updated":"2024-04-24T06:16:30.715991+00:00"}